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Medical Research Finder

meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Butyrate / Butyric acid & Interleukin-6 (IL-6)

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Butyrate / Butyric acid is known for its anti-inflammatory properties. It can reduce the production of pro-inflammatory cytokines, including Interleukin-6 (IL-6), in various cell types such as macrophages and neutrophils. The microbial metabolite butyrate influences the function of Intestinal mucosal macrophages by [inhibiting histone d…

Il-6-induced survival of colorectal carcinoma cells is inhibited by butyrate through down-regulation of the IL-6 receptor
Yuan et al. 2004
Sodium Butyrate Alleviates Lipopolysaccharide-Induced Inflammatory Responses by Down-Regulation of NF-κB, NLRP3 Signaling Pathway, and Activating Histone Acetylation in Bovine Macrophages
Jiang et al. 2020b Front Vet Sci 7: 579674
The Divergent Immunomodulatory Effects of Short Chain Fatty Acids and Medium Chain Fatty Acids
Sam et al. 2021 Int J Mol Sci 22(12): 6453
The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition
Chang et al. 2014 Proc. Natl. Acad. Sci. U. S. A. 111: 2247–2252

7/1/2026