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The current research direction for treating patients with EGFR mutations focuses on the following aspects: uncommon EGFR mutation subtypes, brain metastases, and EGFR TKI-based combination therapy.
Chemotherapy followed with osimertinib brings about the best disease-free survival.
TKIs such as first (erlotinib and gefitinib), second (dacomitinib and [afatinib](brain…