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A randomized controlled trial evaluating VSL#3 TM powder (450 billion lyophilized bacteria/day) or placebo in 25 patients with Diarrhea-predominant Irritable Bowel Syndrome (IBS) (IBS-D) (1)
Pre- and post-treatment gastrointestinal transit measurements (1)
The mean gastrointestinal transit measurements, bowel function scores, and satisfactory global symptom relief showed no significant differences between the two treatment groups, both before and after therapy. Abdominal bloating was reduced with VSL#3 but not with placebo (1)
VSL#3 seems promising for relieving abdominal bloating in patients with diarrhea-predo…