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Tryptophan (Trp) metabolites are important in colorectal cancer (CRC). They work through complex mechanisms. The chemopreventive effects of statins on colorectal cancer are mediated by tryptophan catabolites derived from the microbiota. Atorvastatin treatment of Colorectal cancer (CRC) enriches Limosilactobacillus reuteri in Colorectal cancer (CRC) patients. Its metabolite, [Indole-3-lactate (ILA)](brain://rzv0Lz…