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Medical Research Finder

meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Lactiplantibacillus plantarum & Major depressive disorder / Major Depression / Depressive episode (MDD)

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The evidence appears to be limited to a small number of strain-specific studies (1)

(1) Godzien et al. 2025 J Affect Disord 368:180-190

Probiotic Lactobacillus plantarum 299v supplementation in patients with major depression in a double-blind, randomized, placebo-controlled trial: A metabolomics study
Godzien et al. 2025 J Affect Disord 368:180-190
Psychophysiological Effects of Lactobacillus plantarum PS128 in Patients with Major Depressive Disorder: A Preliminary 8-Week Open Trial
Chen et al. 2021 Nutrients 13(11): 3731

7/1/2026