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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Depressive disorders / Mood & Neurotrophin-3 (NT-3)

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Neurotrophin-3 (NT-3) appears to be a plausible but still unvalidated player in depressive disorders: current literature links it to synaptic plasticity, monoamine systems, neurogenesis, BDNF signaling, and HPA-axis regulation, but the evidence base is much thinner and less consistent than for BDNF
Pae et al. 2008 Int J Neurosci 118(11): 1515-22
Neto et al. 2011 Curr Neuropharmacol 9(4): 530-52
de Miranda et al. 2020 Expert Opinion on Therapeutic Targets 24: 1225-1238

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References (Sources)

Does neurotropin-3 have a therapeutic implication in major depression?
Pae et al. 2008 Int J Neurosci 118(11): 1515-22
Review
Is neurotrophin-3 (NT-3): a potential therapeutic target for depression and anxiety?
de Miranda et al. 2020 Expert Opinion on Therapeutic Targets 24: 1225-1238
Review
Neurotrophins role in depression neurobiology: a review of basic and clinical evidence
Neto et al. 2011 Curr Neuropharmacol 9(4): 530-52
Review

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Depressive disorders / Mood & Neurotrophin-3 (NT-3)

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