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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Cancer genes / Cancer drivers

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The PCAWG Consortium aggregated whole-genome sequencing data from 2,658 cancers across 38 tumor types, generated by the ICGC and TCGA projects.
Li et al. 2020c

Genes with standard therapeutic implications are: ALK-,BRAF-, EGFR-, ERBB2-targetable kinases and genes that play a role in maintaining DNA integrity (BRCA1 & BRCA2)
Chakravarty et al. 2018…

References (Sources)

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes
Rheinbay et al. 2020
Genomic basis for RNA alterations in cancer
PCAWG Transcriptome Core Group et al. 2020
Mammaprint TM: a comprehensive review
Brandão et al. 2019 Future Oncology 15: 207-224
Review
OncoKB: A Precision Oncology Knowledge Base
Chakravarty et al. 2018
The evolutionary history of 2,658 cancers
Gerstung et al. 2020
The repertoire of mutational signatures in human cancer
Alexandrov et al. 2020
WNT as a Driver and Dependency in Cancer
Parsons et al. 2021 Cancer Discovery 11: 2413
Review

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7/1/2026

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Cancer genes / Cancer drivers

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