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In the context of Fluorouracil (5-FU) & Keratosis actinica, topical fluorouracil (5‑FU) is approved for the treatment of keratosis actinica by the FDA and is also approved in topical formulations in Europe; this is a labeled dermatologic indication distinct from its systemic oncology uses.
The randomized clinical trial, identified as NCT02281682, demonstrated that 12 months following the conclusion of treatment for patients wi…