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Medical Research Finder

meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Gastroparesis & Pathogenicity / Pathology

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In gastroparesis, there is a depletion of Interstitial Cajal Cells (ICCs) throughout the stomach, more prominently in the pylorus.

Shanker et al. 2021

Studies have shown increased smooth muscle fibrosis and decreased enteric neurons in gastroparesis.

Bashashati & McCallum 2015 J Neurogastroenterol Motil. 21(4): 486–93
Moraveji et al. 2016 Neurogastroenterol Motil. 28(7): 1048–54.

Remarkably, gastric dysrhythmias are more common during nausea.

Koch 2014 Exp Brain Res. 232(8): 2553–61
O'Grady & Abell 2015 Gastroenterol Clin…

Gastric arrhythmias in gastroparesis: low and high resolution mapping of gastric electrical activity
O'Grady & Abell 2015 Gastroenterol Clin N Am. 44(1): 169–84
Gastric dysrhythmias: a potential objective measure of nausea
Koch 2014 Exp Brain Res. 232(8): 2553–61
Review
Gastric Electrical Stimulation for Treatment of Refractory Gastroparesis: the Current Approach to Management
Shanker et al. 2021
Gastroparesis Updates on Pathogenesis and Management
Liu & Abell 2017 Gut Liver 11: 579-589
Review
Is interstitial cells of Cajalopathy present in gastroparesis?
Bashashati & McCallum 2015 J Neurogastroenterol Motil. 21(4): 486–93
Review
Nausea and Vomiting in 2021
Heckroth et al. 2021
Review
Pathophysiology of gastroparesis syndromes includes anatomic and physiologic abnormalities.
Abell et al. 2020 Dig Dis Sci. 66: 1127-1141

7/1/2026