Neuroimmune interactions

How can neuroimmune interactions be described?

Barrier tissues are interfaces where neural and immune systems work together. Neurons and immune cells form networks to sense environmental cues, pathogen signals, and tissue stress. The role of neurotransmitters and neuropeptides in neuroimmune circuits is:

• Regulate pathogen clearance


• Preserve tissue integrity during infection


• Modulate allergic and autoimmune responses


• Support tissue regeneration (1)

What is the purpose of the interaction between the neural and immune systems?

These networks adjust immunity and maintain homeostasis: defense, inflammation, and repair (1)

References:

(1) Gu et al. 2026 Cell Reports 45: 1

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