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There is evidence from clinical trials suggesting that propolis may help improve glycemic control in individuals with Type 2 Diabetes (T2D). However, the current data supports its use only as an adjunctive, complementary therapy. It is recommended that larger and longer-term trials be conducted before any firm recommendations can be made.
The systematic review and meta-analysis CRD42024577722 were conducted using multiple databases up to May 2025, assessing the effects of propolis supplementation. The study included 12 randomized controlled trials with 731 participants. Results showed that propolis **significantly increased HDL-C levels and reduced LDL-C, triglycerides, fasting blood sugar,…