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Inhibitory effects mean the impairment of pro-inflammatory functions of immune cells:
• by downregulating Tumor Necrosis Factor alfa (TNF-alfa) and Interleukin-12 (IL-12) in Dendritic Cells (DCs), macrophages/monocytes, hepatocytes due to inhibition of NFKB-dependent transcription of pro-inflammatory genes
• by inhibition of the production of the pro-inflammatory cytokine osteopontin by [NKT cells](brain://eV8-tp-xGkK-pFNo_55Aww/NaturalKillerTCellNKTCe…