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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

AuthorsReferences (Sources)

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Alzheimer’s Disease (AD) & Bile Acids / Bile Salts

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Contents

Numerous experimental and clinical studies conﬁrm the Bile Acids / Bile Salts involvement in the pathogenesis of Alzheimer’s Disease (AD)
Pan et al. 2017 Metabolites 7: 28
MahmoudianDehkordi et al. 2019 Alzheimer’s Dement. 15: 76-92
Nho et al. 2019 Alzheimers Dement 15: 232-244
Baloni et al. 2020 Cell Rep Med 1: 100138
Grant & DeMorrow 2020 Int J Mol Sci 21: 5982
Jia et al. 2020 Med Res Rev 40: 1496-1507
Varma et al. 2021 PLoS Med 18: e1003615

Secondary Bile Acids / Bile Salts can cross the BBB and are neuroactive
Monteiro-Cardoso et al. 2021 NeuroMol. Med. 23: 99-117

Experimental and clin…

References (Sources)

Altered bile acid proﬁle associates with cognitive impairment in Alzheimer’s disease - An emerging role for gut microbiome.
MahmoudianDehkordi et al. 2019 Alzheimer’s Dement. 15: 76-92
Altered bile acid proﬁle in mild cognitive impairment and Alzheimer’s disease: Relationship to neuroimaging and CSF biomarkers
Nho et al. 2019 Alzheimers Dement 15: 232-244
Bile acid signaling in neurodegenerative and neurological disorders
Grant & DeMorrow 2020 Int J Mol Sci 21: 5982
Bile Acids: A Communication Channel in the Gut-Brain Axis
Monteiro-Cardoso et al. 2021 NeuroMol. Med. 23: 99-117
Expert insights: The potential role of the gut microbiome-bile acid-brain axis in the development and progression of Alzheimer’s disease and hepatic encephalopathy
Jia et al. 2020 Med Res Rev 40: 1496-1507
Metabolic network analysis reveals altered bile acid synthesis and metabolism in Alzheimer’s disease
Baloni et al. 2020 Cell Rep Med 1: 100138
Metabolomic proﬁling of bile acids in clinical and experimental samples of Alzheimer’s disease
Pan et al. 2017 Metabolites 7: 28

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