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In cancer, Podocalyxin-like protein (PODXL) has been associated with an aggressive tumor phenotype and poor prognosis in various types of malignancies. It interacts with different proteins to promote cancer progression through various signaling pathways such as PI3K/AKT, NFKB, and MAPK/ERK pathways
High expression of Podocalyxin-like protein (PODXL) has been linked to worse overall survival, disease-specific survival, and disease-free survival in cancer patients. It serves as an unfavorable predictor of patient outcomes and is considered a promising prognostic biomarker, especially in European populations
In colon cancer, Podocalyxin-like protein (PODXL) has …