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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Chemotherapy (CT) & Breast cancer / Mammacarcinoma (TNBC)

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For Breast cancer / Mammacarcinoma (TNBC) chemotherapy is a core systemic treatment because TNBC lacks estrogen, progesterone, and HER2 targets, so hormone therapy and HER2-directed therapy are generally not useful. In practice, chemotherapy is used in early-stage disease either before surgery (neoadjuvant) or after surgery (adjuvant), and it is also commonly the first systemic treatment in metastatic TNBC.

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References (Sources)

Comparative Effectiveness of Palliative Chemotherapy in Metastatic Breast Cancer: A Real‐World Evidence Analysis
Feinberg et al. 2020 The Oncologist 25: 319-326
Harmonizing gene signatures to predict benefit from adjuvant chemotherapy in early breast cancer
Criscitiello et al. 2019 Current Opinion in Oncology. 31(6):472-479
Role of dose-dense chemotherapy in high-risk early breast cancer
Blondeaux et al. 2019 Current Opinion in Oncology. 31(6):480-485

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Chemotherapy (CT) & Breast cancer / Mammacarcinoma (TNBC)

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