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How fungal dysbiosis contributes to alcohol-associated liver disease is unclear. Zeng et al. find that C. albicans-specific Th17 cells increase in the blood and liver of patients with alcohol-associated liver disease. In mice, C. albicans-specific Th17 cells migrate from the intestine to the liver, where they contribute to ethanol-induced liver disease
Alcohol increases intestinal C. albicans-specific Th17 cells that migrate to the liver
Zeng et al. 2023 Cell Hos…