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A randomized, double-blind, placebo-controlled phase II treatment trial to assess the efficacy and safety of a novel aerosol formulation of levofloxacin (MP-376, Aeroquin) in 151 patients with Cystic Fibrosis (CF) with chronic Pseudomonas aeruginosa infection
Primary outcome measures:
Change in Pseudomonas aeruginosa density
Conclusion:
Nebulized MP-376 was well tolerated. It demonstrated significant clinical efficacy in heavily treated patients with CF who have PA lung infection.
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