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A multicentre, open-label, single-arm, phase II trial evaluating Loncastuximab tesirine in patients with relapsed or refractory Large B-cell lymphoma (LBCL) / Diffuse Large B-Cell Lymphoma (DLBCL) after two or more multiagent systemic treatments
Primary Outcome Measures:
Overall response rate (ORR)
The authors concluded that Loncastuximab tesirine has substantial single-agent antitumor activity and produces durable responses with an acceptable safety profile. Thus, it potentially offers a new therapeutic option for heavily pretreated patients with relapsed or refractory Diffuse Large B-Cell Lymphoma (DLBCL)
Caimi et al. 2021 The Lancet Oncology 22: 790-800
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