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The interaction between Enterococcus faecalis and Th17 cells involves both pathogenic and potentially beneficial effects. Enterococcus faecalis can activate T helper 17 cell (Th17), leading to inflammation and immune responses that can be detrimental in chronic infections. However, under certain conditions, Enterococcus faecalis can also modulate immune responses to reduce inflammation.
The pathogenicity of Enterococcus faecalis is primarily expressed in the activation of the Th17/Treg cell pathway. This activation results in the secretion of cytokines and continuous inflammation, which can lead to multiple organ infections.
The T helper 17 cells (Th17) are essential in developing several allergic diseases.
Zhang et al. 2012 Int J Mol Med. 3…