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Butyrate / Butyric acid can induce apoptosis in a variety of cell types, particularly cancer cells, mainly through inhibition of histone deacetylases and modulation of cellular metabolic and signaling pathways. The inhibition of histone deacetylases (HDACs) leads to hyperacetylation of histones. This promotes gene transcription, which can trigger cell cycle arrest and programmed cell death (apoptosis). This mechanism is significant in can…