Loading…
Please register to continue your trial period!
meRfi Microbiome provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.
Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.
Start your free trial and transform your understanding of the gut microbiota today!
To determine the clinical and cost effectiveness of a 7-day course of oral prednisolone (steroid) on improving hearing loss over the short term in children with bilateral OME, as diagnosed at an ENT outpatient clinic, who have had symptoms attributable to OME present for at least 3 months, and current significant hearing loss (demonstrated by audiometry).
Primary outcome measures:
Acceptable hearing at five weeks from randomisation (four weeks after conclusion of treatment), where acceptable hearing is defined as less than 20 dB averaged at 0.5, 1, 2 and 4 kHz in at least one ear in children aged 3-8 years, and less than 25 dB averaged at 0.5, 1, 2 and 4 KHz by sound field VRA in children aged under 3 years. These thresholds are based on national guidelines.
…