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dietary compounds generates a vast array of microbiome-dependent metabolites (MDMs), which are highly variable between individuals
Guthrie et al. 2022 Cell Host & Microbe 30: 863-874
The uremic MDMs (uMDMs)) Phenylacetylglutamine (PAG), p-cresol sulfate (PCS, and indoxyl sulfate (IS) accumulate during renal failure and are associated with poor outco…