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The inflammatory reflex is a neural circuit that regulates the immune response to injury and invasion. Like all reflexes, it consists of an afferent and an efferent arc.
The sensory afferent arc of the inflammatory reflex is activated by Cytokines. These cytokines signal the presence of inflammation or infection to the brain
The motor or efferent arc transmits action potentials through the vagus nerve to suppress cytokine production. Increased signaling in the efferent arc inhibits inflammation and prevents or…