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The Vasoactive intestinal protein (VIP) receptor Vipr2 agonist BAY-559837 suppresses IL-22 production in CCR6+ ILC3s from mice both in vitro and in vivo. Conditional depletion of vasoactive intestinal protein (VIP) receptor Vipr2 in Group 3 ILCs (ILC3) increases the number of IL-22-producing CCR6+ ILC3s relative to control mice
Enterocytes / Intestinal Epithelial Cells (IECs) release [Inte…