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Targeting inflammation and fibrosis early combinations of antifibrotic drugs (e.g., pirfenidone) with immunomodulatory agents (e.g., mycophenolate mofetil) are investigated.
Traditional therapies for Systemic Sclerosis (SSc) center on immunosuppressive and cytotoxic agents. A new cadre of therapies is borne from improved understandings of SSc pathobiology and target the inflammatory-fibrotic pathways.
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