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Several clinical studies have evaluated Lacticaseibacillus casei containing preparations in irritable bowel syndrome (IBS), but evidence is mixed and often strain‑specific (1, 2).
This randomized, double-blind, placebo-controlled intervention trial revealed that following the probiotic treatment with Lacticaseibacillus casei Shirota , there was no observed improvement of 30% in MSS after 8 weeks (1).
(1) Thi…