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Iron can be used for the synthesis of heme, which serves as a prosthetic group for metalloenzymes and as an oxygen-binding unit of hemoglobin.
Hemoglobin serves several critical functions:
In senescent erythrocytes, hemoglobin is meticulously recycled by macrophages within the reticuloendothelial system. The enzyme heme oxygenase (HO-1) plays a crucial role in this …