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The human gut microbiota's altered profile is closely linked to cirrhosis and its complications (1). Gut microbial dysbiosis is associated with the progression of various liver diseases, including alcoholic liver disease, non-alcoholic fatty liver disease, and liver cirrhosis. This dysbiosis also promotes the progression of hepatocellular carcinoma (HCC) in experimental mouse models (2, 3).
The primary microbiota linked to fibrosis severity…