VE303

What is VE303?

VE303 is a defined bacterial consortium that originates from human stools and is produced from clonal cell banks (i.e., a synthetic oral capsule) developed by Vedanta Biosciences
Benech et al. 2024 Clinical Microbiology and Infection 30: 462-468
Gawey & Khanna 2023 Gastroenterol Hepatol (N Y) 19(6): 319-328

What bacterial strains does VE303 contain?

It consists of 8 well-characterized Clostridioides strains (including 5 strains from Clostridia cluster XIVa, 2 strains from cluster IV, and 1 strain from cluster XVII) that are considered commensal and do not produce toxins
Louie et al. 2023 JAMA 329: 1356
Dsouza et al. 2022 Cell & Host Microbe 30: 583–598
Garber 2020 Nat. Rev. Drug Discov. 19: 655–656

see also:
Partial-community (functional-group) consortia