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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Chemotherapy (CT) & Immunogenic cell death (ICD)

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Immunogenic cell death (ICD) is induced by doxorubicin , mitoxantrone , gamma-irradiation. It depends on induction of Endoplasmic reticulum (ER) stress.
Krysko et al., 2012

Anthracyclin-treated tumor cells are particularly effective in eliciting an anticancer immune response, whereas other DNA-damaging agents such as etoposide and mitomycin C do not induce [Immunogenic cell death (ICD)](brain://WmKNIEvUNUK9eYxY8…

References (Sources)

Calreticulin exposure dictates the immunogenicity of cancer cell death
Obeid et al. 2007
Immunogenic cell death and DAMPs in cancer therapy
Krysko et al., 2012

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7/1/2026

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Chemotherapy (CT) & Immunogenic cell death (ICD)

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