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In the context of Dacarbazine & Melanoma (cutaneous), Dacarbazine is approved by both FDA and EMA for the treatment of metastatic Melanoma (cutaneous) (1). In 1999, Dacarbazine remains the reference standard treatment for stage IV melanoma (2, 5).
But in the meantime, standard treatment of cutaneous melanoma is stage‑dependent and combines surgery (wide local excision ± sentinel node biopsy) with risk‑adapted systemic therapy (immunotherapy or BRAF/MEK–targeted therapy) in stage III–IV disease (3,…