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Primary Purpose : Treatment
Allocation : Randomized
Interventional Model : Parallel Assignment
Masking : Triple (ParticipantCare ProviderInvestigator)
Primary outcome measures:
Annualized Rate of Severe Exacerbation Events During The 52-Week Treatment , the absolute change from baseline to week 12 in the forced expiratory volume in 1 second (FEV1 ) before bronchodilator use
The authors concluded that in this trial, patients who received dupilumab had significantly lower rates of severe asthma exacerbation than those who received placebo. They also had better lung function and asthma control. More significant benefits were seen in patients with higher baseline levels of [eosinophils](brain://cmCZ8Oxr60SxBh2-ocst-Q/Eosino…