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Amyloid-beta (Aß, Abeta) is also a ligand of Toll-Like Receptors (TLRs) (e.g., on the surface of microglia), which, under certain conditions, can initiate the inflammatory process in the gut and the brain, leading to the development of neurodegenerative diseases, including Alzheimer's disease (AD).
see also:
[Microglia & Toll-like receptors (TLRs)](brain://TiF6NQnQQkeVq8BkXYd6Ow/M…