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A sustained biomarker discovery and validation effort has been led by the Mount Sinai Acute GVHD International Consortium (MAGIC)), a group of HCT centers that carefully monitor clinical GVHD according to consensus criteria and who collect serum at regular intervals during the course of disease and its treatment.
The MAGIC algorithm probability (MAP) combines the serum levels of IL-1 Receptor-like 1 (IL1RL1) and REG III alfa to provide a single value that predicts an individual patient’s ri…