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A trial evaluating Bifidobacterium longum BB536 + Fructooligosaccharides (FOS) + Lactobacillus acidophilus NCFB 1748 vs Fructooligosaccharides (FOS) in healthy volunteers during a 7-day course of Cefpodoxime, administered twice daily.
Outcome measures:
Reduction in Aerobic Microorganisms, Increase in Intestinal Yeasts, Decrease in Anaerobic Microorganisms, Presence of Clostridium difficile, Colonization by Bifidobacterial Strains, Recovery of Administered Strains
Conclusion:
This study highlights the potential impact of probiotics and oligofructose on maintaining intestinal microflora balance during antibiotic treatment.
Orrhage et al. 2000 J Antimicrob Chemother 4…