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Moderate-certainty evidence supports selected live probiotics, used concurrently with antibiotics, to prevent antibiotic-associated diarrhea; however, probiotics exhibit strain-specific effects, necessitating separate evaluations of each strain's clinical impact (5). The best-supported named agents are Lactobacillus rhamnosus GG and Saccharomyces boulardii, with stronger effects at higher doses and in populations at higher baseline risk (4, 5).
Antibiotics can change the balance of microbes, which often leads to antibiotic-associated diarrhea (AAD). P…