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Goblet cells are simple columnar epithelial cells, secret mucus contributing to host defense by providing a physical separation between the epithelial and gut microbiota, promoting the separation of the lumen's bacteria and preventing colonization of the epithelium
Damage of Goblet Cells causes loss of IEC integrity and permits the translocation of gut microbes and all gut antigenic load (metabolites, peptides, and proteins) into the submucosa, [lymph nodes](brain://u…