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Research has indicated that bacteria present in the intestinal lumen might play a role in the development of Crohn's disease. As a potential alternative to antibiotics, probiotics are being considered for their beneficial effects (1)
It is a single-centre, 52‑week, prospective, randomized, double‑blind, placebo‑controlled prevention trial studying Lacticaseibacillus rhamnosus GG (LGG) (6 billion cfu per sachet, 1 sachet twice daily) or placebo in 37 analyzed patients to prevent postoperative recurrence of Crohn’s disease after curative resection (1)
Endoscopic recurrence at 12 months, Rutgeerts score ≥2 (1)