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Mutation B-RAF V600 in 40-70% of all BRAF mutations
Mutations in BRAF also in Hairy Cell Leukemia (HCL) (BRAF m), Colorectal cancer (CRC) (BRAF m), Ovarian Cancer (BRAF m), Thyroid cancer (BRAF m)
BRAF mutations also in many types of benign melanocytic nevi and benign nodal nevi
BRAF mutation activates Raf/MEK/ERK pathway in multiple tumor types
see also:
B-RAF V600…