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Aspirin (acetylsalicylic acid: ASA) has been studied in the context of Lynch syndrome (LS) or hereditary nonpolyposis colorectal cancer (HNPCC). Research has shown that aspirin and low-dose nitric oxide–donating aspirin (NO-ASA) can increase the lifespan in a Lynch syndrome mouse model, potentially representing a chemopreventive option for LS/HNPCC patients…