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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Epithelial sodium channel (ENaC)

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Epithelial sodium channel (ENaC) is an attractive therapeutic target to rehydrate Cystic fibrosis (CF) ASL that may serve as a monotherapy or function in parallel with other treatments.
Moore & Tarran 2018 Expert Opin.Ther.Targ. 22: 687-701

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References (Sources)

PPARγ-induced stimulation of amiloride-sensitive sodium current in renal collecting duct principal cells is serum and insulin dependent
Chraïbi & Renauld 2014 Cell Physiol Biochem 33: 581-593
sgk: an essential convergence point for peptide and steroid hormone regulation of ENaC-mediated Na+ transport
Faletti et al. 2002 Am J Physiol Cell Physiol 282: C494-C500
The epithelial sodium channel (ENaC) as a therapeutic target for cystic fibrosis lung disease
Moore & Tarran 2018 Expert Opin.Ther.Targ. 22: 687-701
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Epithelial sodium channel (ENaC)

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