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Primary Purpose : Treatment
Allocation : N/A
Interventional Model : Single Group Assignment
Masking : None (Open Label)
Primary outcome measures:
Probability of Progression-free Survival (PFS) at 2 Years
The authors' conclusion was: Intensification of adjuvant treatment adding panitumumab to cisplatin chemoradiotherapy (CRT) is tolerable and demonstrates improved clinical outcomes for high-risk, resected, HPV-negative head and neck squamous cell carcinoma patients. Further targeted monoclonal antibody combinations are warranted.
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