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Medical Research Finder

meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Alfa-Synuclein (SNCA) & Appendix

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Interestingly, a 2021 meta-analysis demonstrated no signiﬁcant difference in the emergence of Morbus Parkinson / Parkinson's Disease (PD ) between patients with and those without an appendectomy history
Ishizuka et al. 2021 Am Surg, doi: 10.1177/ 0003134821989034

A large, nested control study conducted by Liu et al. also concluded that an appendectomy was associated with a lower risk of Morbus Parkinson / Parkinson's Disease (PD)
Liu et al. 2020m Front Neurol 11: 510

Patients with [appendectomies](brain://7uveMzSmTEqVg…

Appendectomy does not increase the risk of future emergence of Parkinson’s disease: A meta-analysis.
Ishizuka et al. 2021 Am Surg, doi: 10.1177/ 0003134821989034
Appendectomy, tonsillectomy and Parkinson’s disease risk: A Swedish register-based study.
Liu et al. 2020r Front Neurol 11: 510
The vermiform appendix impacts the risk of developing Parkinson's disease.
Killinger et al. 2018 Science translational medicine 10 eaar5280

7/1/2026