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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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CMTX-101

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CMTX-101, a humanized monoclonal antibody, actively treats Bacterial Biofilm / Microbial Biofilm (BF) infections. It targets a universal component of bacterial biofilms, rapidly breaking them down regardless of the pathogen. CMTX-101 operates through three mechanisms:

Sensitizes bacteria to antibiotics

Activates the host's immune system

Suppresses site-specific tissue inflammation

CMTX-101 effectively treats infections, especially amid rising antibiotic resistance, by destroying biofilms and making bacteria accessible to other therapies.
Rogers et al. 2022 Antibiotics (Basel) 11(1): 104

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References (Sources)

Crumbling the Castle: Targeting DNABII Proteins for Collapsing Bacterial Biofilms as a Therapeutic Approach to Treat Disease and Combat Antimicrobial Resistance
Rogers et al. 2022 Antibiotics (Basel) 11(1): 104

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7/1/2026

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