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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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MRX-8 is a novel polymyxin B analog developed for the treatment of infections caused by Gram-negative bacteria, including Pseudomonas aeruginosa.
Lepak et al. 2020 Antimicrob Agents Chemother 64(11): e01517-20
Duncan et al. 2022 Antimicrob Agents Chemother 66(5): e0013922

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References (Sources)

In Vitro Potency and Spectrum of the Novel Polymyxin MRX-8 Tested against Clinical Isolates of Gram-Negative Bacteria
Duncan et al. 2022 Antimicrob Agents Chemother 66(5): e0013922
Pharmacodynamic Evaluation of MRX-8, a Novel Polymyxin, in the Neutropenic Mouse Thigh and Lung Infection Models against Gram-Negative Pathogens
Lepak et al. 2020 Antimicrob Agents Chemother 64(11): e01517-20

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