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Fluorouracil (5-FU)-based chemotherapy is frequently associated with diarrhoea.
It is an open-label, randomized clinical phase III prevention trial evaluating Guaran / Guar gum (11 g guar gum per day) + Lacticaseibacillus rhamnosus GG (LGG) ((1–2 x 10^10 per day) in 148 eligible patients with colorectal cancer under monthly 5-FU and leucovorin bolus injections for for 24 weeks
Frequency of severe diarrhoea
Osterlund et a…