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Clinical trial of the effect of probiotic supplementation compared with the placebo on metabolic profiles in patients with Parkinson's
Primary outcome measures:
High sensitivity C-reactive protein (hs-CRP); Unified Parkinson's disease rating scale (Physical Examination by Neurologist)
Our study evidenced that 12 weeks of probiotic consumption by individuals with PD had useful impacts on Movement Disorders Society–Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) (improvement in motor signs and symptoms) and few metabolic profiles. These improvements corresponded with lower serum levels of C-reactive protein, a marker of systemic inflammation, higher levels of the antioxidant glutathione, and increased insulin sensitivity
Tamtaji et al. 2019 Clin. Nutr. 38: 1031-1035…