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In the context of Vinflunine & Bladder cancer, Vinflunine was approved by the European Medicines Agency in 2009 as second‑line chemotherapy for patients with advanced or metastatic transitional cell carcinoma of the urothelial tract after failure of a platinum‑based regimen (1). Multiple European “real‑world” series explicitly state that vinflunine is the only chemotherapy registered in Europe for second‑line treatment of platinum‑refractory bladder cancer (2, 3, 4).
In a retrospective analysis of the French multi-centre CURVE study, which evaluated the efficacy and safety of Vinflunine (VFL) unde…