Loading…
Please register to continue your trial period!
meRfi Microbiome provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.
Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.
Start your free trial and transform your understanding of the gut microbiota today!
Macroautophagy / Autophagy is upregulated in many cancers and supports their growth, survival, and malignancy in a tumor cell-autonomous fashion. Additionally, host autophagy promotes Tumor growth by:
Maintaining a supply of essential nutrients.
Suppressing innate and adaptive antitumor immune responses
Autophagy is also upregulated in response to cancer therapy, which confers treatment resistance. Therefore, autophagy represents a cancer vulnerability, and its inhibition is under investigation as a novel therapeutic approach
Inhibition of autophagy leads to decreased Tumor growth.
Studies have found that aut…