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Medical Research Finder

meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Depressive disorders / Mood & Hypothalamic–pituitary–adrenal axis (HPA axis)

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Atypical depression is associated with a hypofunction of the HPA axis
Gawlik-Kotelnicka et al. 2021 J. Clin. Med. 10: 1342

In typical depression, the axis is upregulated with excess release of cortisol.
Aizawa et al. 2016 J. Aﬀect. Disord. 202: 254-257

Possible association of Biﬁdobacterium and Lactobacillus in the gut microbiota of patients with major depressive disorder
Aizawa et al. 2016 J. Aﬀect. Disord. 202: 254-257
The Inﬂuence of Probiotic Supplementation on Depressive Symptoms, Inﬂammation, and Oxidative Stress Parameters and Fecal Microbiota in Patients with Depression Depending on Metabolic Syndrome Comorbidity—PRO-DEMET Randomized Study Protocol
Gawlik-Kotelnicka et al. 2021 J. Clin. Med. 10: 1342

7/1/2026